Peel + Boost: a new generation of synergistic clinical solutions

At the intersection of dermatological precision and formulation innovation, Dermaceutic introduces Peel + Boost, a new dual-level treatment approach designed to optimize and sustain results. 

Combining a professional superficial peel with a high-tech micropeel, Peel + Boost represents a meaningful shift in how chemical exfoliation can be delivered, extended, and maintained, both in-clinic and at home.

A dual-level treatment concept

Peel + Boost is built around a simple but clinically powerful principle: pair a professional superficial peel with its corresponding micropeel booster to create a coherent, synergistic treatment approach that works across two timeframes simultaneously.

The micropeel delivers immediate in-clinic correction through high-performance exfoliation of the stratum corneum. The Boost extends and amplifies this correction through a patented* microemulsion technology that enables controlled-release active derivatives to continue working after the patient leaves the clinic.

Together, they combine immediate in-clinic correction with prolonged efficacy to optimize both short- and long-term results, visible from the first session. The active ingredient continuity between each Peel and its corresponding Boost, a professional-grade acid paired with its derivative, creates a coherent treatment logic that is both scientifically rigorous and practically streamlined.

We have developed three dedicated Peel + Boost duos, each precisely designed to address a specific skin concern: acne-prone and oily skin with Salic Peel + Boost, signs of skin aging and loss of firmness with Retinic Peel + Boost, and hyperpigmentation and uneven skin tone with Tranex Peel + Boost.

PEEL: micro peels powered by multi-generational acids

The superficial peel is the first action of Peel + Boost. It is powered by a modern, science-led combination of multi-generational acids that bridges the gap between high-performance exfoliation and optimal skin tolerance, setting a new standard in professional dermatological care.

Unlike single-acid peels, Dermaceutic's layered acid approach enables each peel to target several key levels in the biological pathway of each condition, focus performance to deliver optimal and visible results, and adapt treatments across indications, skin types, and phototypes.

The multi-generational acid framework draws on three generations of exfoliating molecules. First-generation AHAs are small, water-soluble molecules driving efficient surface exfoliation, radiance, and texture smoothing. Second-generation BHAs are oil-soluble molecules that exfoliate pores to reduce comedones, inflammation, and excess oil. Next-generation PHAs are larger-size polyhydroxy acids enabling controlled, low-irritation resurfacing with hydrating and barrier-supportive benefits.

Each peel combines acids selected for their complementarity and skin affinities to deliver fast, precise, and indication-specific in-clinic correction.

Salic Peel combines salicylic acid, glycolic acid, and bentonite, acting on the stratum corneum and within pores to limit surface buildup of oxidized sebum. Its multi-acid profile targets dead skin cell exfoliation and sebum absorption through an AHA, BHA, and clay combination.

Retinic Peel is formulated with retinal extract, lactic acid, lactobionic acid, and resveratrol, acting on the stratum corneum to stimulate cellular turnover and skin renewal. It delivers an AHA, PHA, and retinoid approach targeting cell turnover stimulation and antioxidant action.

Tranex Peel features tranexamic acid, gluconolactone, phytic acid, and potassium azeloyl diglycinate, promoting gentle exfoliation and enhancing the penetration of depigmenting and antioxidant agents. Its PHA, antioxidant, and depigmenting agent combination targets melanin pathway inhibition and antioxidant action.

BOOST: micropeels powered by patented microemulsion technology

The micropeel is a clinically engineered post-peel booster and the second action of Peel + Boost. Powered by a patented* microemulsion technology, it reflects Dermaceutic's commitment to next-generation formulation innovation.

Inspired by the self-assembling logic of biological membranes, this exclusive technology mimics natural systems to deliver active ingredients intelligently, efficiently, and safely, even on sensitive skin. Developed through advanced in-house R&D and protected by Dermaceutic's first patent*, it leverages the spontaneous organization of oil, water, and surfactant molecules into a sophisticated delivery system engineered with nanometric precision. It is a true formulation achievement and reflects Dermaceutic's expertise in translating complex biological principles into high-performance skincare innovation.

Four key technical properties define this microemulsion technology. 
1.    An ultra-fine droplet size of less than 100 nm enables enhanced skin penetration. 
2.    Thermodynamic stability ensures consistent performance over time. 
3.    Controlled release delivers prolonged efficacy with reduced irritation potential. 
4.    High bioavailability allows actives to reach their target with precision.

Applied in-clinic after the peel and continued at home by the patient, each micropeel combines targeted active derivatives selected for their complementary mechanisms with the peel acids to amplify, prolong, and maintain indication-specific results.

Salic Boost contains lipo-hydroxy acid as a salicylic acid derivative, succinic acid, and star anise extract. Thanks to microemulsion, actives are delivered directly into the epidermis, targeting surface keratinocytes and sebaceous follicles for an extended comedolytic and antibacterial effect. Its actions center on comedolytic activity and sebum regulation.

Retinic Boost combines retinoic acid ester as a retinoid derivative, acetyl hexapeptide-8, and hydroxyproline. It delivers retinoid derivatives, amino acids, and peptides directly into the epidermis via microemulsion, supporting collagen synthesis and cellular renewal. Its actions center on collagen stimulation and skin remodeling.

Tranex Boost is formulated with a tranexamic acid derivative, glutathione, and phenylethyl resorcinol. It delivers actives directly into the epidermis via microemulsion, targeting melanocytes and keratinocytes to inhibit melanin production and limit pigment recurrence. Its actions center on melanin inhibition and antioxidant protection.

Clinically proven efficacy

Each Peel + Boost duo, as part of a 4-step in-clinic protocol, has been evaluated through in vivo clinical studies conducted by a European independent contract research organization. 

Salic Peel + Boost provides a synergistic approach to acne-prone skin management by combining rapid pore-clearing exfoliation with prolonged corrective maintenance to reduce imperfections, excess oil, and inflammation while helping prevent future breakouts.

76% of patients reported that the protocol improves the appearance of acne-prone skin.* 

Anti-imperfection effect highlighted by scoring and counting of inflammatory and retentional lesions:
- Total inflammatory and retentional lesions: -37.3%
- Comedones and microcysts: -24.2%
- Papulae: -39% 
- Pustules: -63.2 %

Efficacy on acne-related items highlighted by clinical scoring:
- Skin shininess: -22.2%
- Imperfection: -16.6% 
- Pore visibility: -9.3%

*In vivo study of Salic Peel + Salic Boost complete protocol with Advanced Cleanser, D Scrub, Foamer 15, Repair Ceutic, Sun Ceutic 50+ on 21 patients after 3 sessions. European independent contract research organization.

Retinic Peel + Boost offers a multifaceted anti-aging approach by combining powerful resurfacing with sustained dermal remodeling support to visibly improve wrinkles, fine lines, texture, and overall skin quality over time.

86% of patients reported that their skin is more lifted after 4 sessions. *

Anti-wrinkle effect highlighted by image analysis - skin microrelief evolution:
- Number of wrinkles: -26.4% 
- Total wrinkle surface area: -32.9% 
- Total wrinkle length: -33.8% 

Efficacy on anti-aging related items highlighted by clinical scoring:
- Skin tone evenness: +46.7% 
- Skin tonicity: +38.2% 
- Skin suppleness: +46.6% 

*In vivo study of Retinic Peel + Retinic Boost complete protocol with Advanced Cleanser, D Scrub, Foamer 15, Repair Ceutic, Sun Ceutic 50+ on 21 patients after 4 sessions.
European independent contract research organization.

Tranex Peel + Boost delivers a comprehensive pigmentation correction strategy by combining immediate exfoliative correction with prolonged brightening action to reduce discoloration and maintain a more even, radiant skin tone over time. 

88% of patients reported that the protocol improves skin tone uniformity.*

Anti-spot effect highlighted by mexametric measurements:
-18.95% melanic index on pigmented treated area vs -14.7% on non-pigmented treated area.

Efficacy on pigmentation related items highlighted by clinical scoring:
- Complexion radiance : +54.7% 
- Complexion uniformity : +61.2%
- Pigment spot intensity : -22.2% 

*In vivo study of Tranex Peel + Tranex Boost complete protocol with Advanced Cleanser, D Scrub, Foamer 15, Repair Ceutic, Sun Ceutic 50+ on 24 patients after 4 sessions. European independent contract research organization.

An expert in-clinic protocol

The Peel + Boost duos are integrated into a complete 4-step in-clinic protocol, scientifically designed to support every phase of the treatment, from preparation to post-peel care.

Step 01 CLEANSE: cleansing foam using Advanced Cleanser and/or micellar water using Oxybiome.

Step 02 PRE-PEEL: refining exfoliant using D Scrub* and/or exfoliating foam using Foamer 5/15. 
*Can be adapted by practitioner depending on the skin condition (avoid mechanical exfoliation on inflammatory acne).

Step 03 PEEL+BOOST: the superficial peel chosen from Salic, Retinic, or Tranex Peel, combined with the corresponding micropeel from Salic, Retinic, or Tranex Boost. 

Step 4 POST-PEEL: soothing recovery mask using Repair Ceutic and sun care using Sun Ceutic 50+.

This protocol offers a standardized yet flexible approach, adaptable to different skin types and indications. It delivers a smoother, more predictable treatment experience for the patient, reinforces the expert role with clinical control at every stage, improves results through synergistic product performance, and enhances patient trust through professional-only steps and expert guidance. It is a ready-to-use protocol compatible with varying levels of expertise and treatment settings.

Practice and patient engagement

The Peel + Boost system is designed for professionals at all expertise levels and practice models, from medical doctors to trained aestheticians. Its exclusive Cliniceuticals micropeels reinforce professional expertise, patient adherence, and create valuable retail opportunities through the at-home Boost continuation.

High tolerance across skin types and phototypes makes the system suitable for personalized solutions across a broad patient population.

Peel + Boost represents a new chapter in professional chemical exfoliation. By pairing multi-generational acid peels with a patented microemulsion-powered booster, Dermaceutic has created a clinically coherent system that addresses the fundamental limitation of traditional peel protocols: results that stop when the patient leaves the clinic.

With Peel + Boost, correction begins in-clinic and continues at home, driven by the same active ingredient logic, amplified by next-generation delivery technology.

This is Skintelligent Science applied to professional practice.

*Pending EU and US patent